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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC23IP All Species: 16.06
Human Site: T186 Identified Species: 35.33
UniProt: Q9Y6Y8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Y8 NP_009121.1 1000 111076 T186 G Y N P Y R H T P G S S R A N
Chimpanzee Pan troglodytes XP_508076 1000 111144 T186 G Y N P Y R H T P G S S R A N
Rhesus Macaque Macaca mulatta XP_001100615 1000 110977 T186 G Y N P Y R H T P G S S R A N
Dog Lupus familis XP_535037 1003 111786 T186 G H N P Y R H T P V S S R A N
Cat Felis silvestris
Mouse Mus musculus Q6NZC7 998 110762 V184 N P Y R H T P V S S R A N P Y
Rat Rattus norvegicus NP_001128331 999 110925 P184 H N P Y R H T P V S S R A N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515025 1007 112022 S193 P Y R H T P I S S R A N P Y I
Chicken Gallus gallus XP_424389 690 77700
Frog Xenopus laevis NP_001087410 1007 112007 V185 H N I Q S S R V N P Y L A P P
Zebra Danio Brachydanio rerio NP_001070847 977 109367 Q184 M A P E L Q Q Q P P S Q T P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796242 926 103546 T190 H R P M P Y P T G G V T P A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.1 91.3 N.A. 86.3 88 N.A. 79.2 39.7 66.3 63.5 N.A. N.A. N.A. N.A. 42.7
Protein Similarity: 100 99.3 98.8 93.4 N.A. 91.4 92.6 N.A. 86.3 51.5 76.4 74.9 N.A. N.A. N.A. N.A. 56
P-Site Identity: 100 100 100 86.6 N.A. 0 6.6 N.A. 6.6 0 0 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 6.6 N.A. 26.6 0 0 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 10 10 19 46 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 37 0 0 0 0 0 0 0 10 37 0 0 0 0 0 % G
% His: 28 10 0 10 10 10 37 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % L
% Met: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 19 37 0 0 0 0 0 10 0 0 10 10 10 37 % N
% Pro: 10 10 28 37 10 10 19 10 46 19 0 0 19 28 19 % P
% Gln: 0 0 0 10 0 10 10 10 0 0 0 10 0 0 10 % Q
% Arg: 0 10 10 10 10 37 10 0 0 10 10 10 37 0 0 % R
% Ser: 0 0 0 0 10 10 0 10 19 19 55 37 0 0 10 % S
% Thr: 0 0 0 0 10 10 10 46 0 0 0 10 10 0 0 % T
% Val: 0 0 0 0 0 0 0 19 10 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 37 10 10 37 10 0 0 0 0 10 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _